Guinea pigs should be handled carefully and gently. Their bodies need your full support in order to prevent injuries. One hand should be placed under the guinea pig’s chest and abdomen, and the other supports its hind legs. Keep your guinea pig close to your chest.
An alternate way to hold your guinea pig is to position them on your chest, with their head facing upward. Place your hand underneath their bottom with the other hand gently positioned over your guinea pig’s back.
Make sure that you pat your guinea pig gently, and try to avoid handing them around loud places.
Some guinea pigs like to be patted in the back only, but others don’t mind wherever you pat them. Here’s Patrice’s feelings on the matter: